反应详情

4-Amino-5-chloro-N-((1-(6-(3,4-dichlorobenzylamino)hexyl)piperidin-4-yl)methyl)-2-methoxybenzamide (1.11 g) as starting compound, acetaldehyde (0.13 ml) and sodium cyanoborohydride (0.3 g) were reacted and treated in the same manner as in Example 136 to give 0.75 g of 4-amino-5-chloro-N-((1-(6-(N-(3,4-dichlorobenzyl)-N-ethylamino)hexyl)-piperidin-4-yl)methyl)-2-methoxybenzamide.

1. customwere reacted
2. additiontreated in the same manner as in Example 136