反应详情

4-Amino-5-chloro-2-methoxy-N-(piperidin-4-ylmethyl)benzamide dihydrochloride (5.20 g) as a starting compound, 5-bromo-1-(4-hydroxyphenyl)-1-pentanone (3.60 g) and potassium carbonate (8.7 g) were reacted and purified in the same manner as in Example 172 to give 3.71 g of 4-amino-5-chloro-2-methoxy-N-((1-(5-(4-hydroxyphenyl)-5-oxopentyl)-piperidin-4-yl)methyl)benzamide, m.p. 154°-156° C.

1. custompurified in the same manner as in Example 172