Hydrochloric Acid → 2-(1-Piperazinyl)-5-propylbenzenesulfonic acid hydrochloride

HRID 344663Notes

Reaction equation

HRID 344663 reaction equation
[ClH:1].[N:2]1([C:8]2[CH:13]=[CH:12][C:11]([CH2:14][CH2:15][CH3:16])=[CH:10][C:9]=2[S:17]([OH:20])(=[O:19])=[O:18])[CH2:7][CH2:6][NH:5][CH2:4][CH2:3]1>C(O)C>[ClH:1].[N:2]1([C:8]2[CH:13]=[CH:12][C:11]([CH2:14][CH2:15][CH3:16])=[CH:10][C:9]=2[S:17]([OH:20])(=[O:18])=[O:19])[CH2:7][CH2:6][NH:5][CH2:4][CH2:3]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 30273132-(1-Piperazinyl)-5-n-propylbenzenesulfonic acid

Product 1

HCID 30273122-(1-Piperazinyl)-5-propylbenzenesulfonic acid hydrochlorideYield 95.4%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a mixed solution of 200 ml of ethyl alcohol and 185 ml of 1 N hydrochloric acid was added 50.0 g of 2-(1-piperazinyl)-5-n-propylbenzenesulfonic acid and the mixture was dissolved by heating. The mixture was condensed under reduced pressure, and precipitated crystals were washed with acetone and dried to give 51.46 g (yield: 95.4%) of the above title product.

Workup

  1. dissolutionthe mixture was dissolved
  2. temperatureby heating
  3. customcondensed under reduced pressure
  4. customprecipitated crystals
  5. washwere washed with acetone
  6. customdried

Sources & evidence

ORD record
ord-d76cb509ad854474bc39f92d9a615bb1
Source dataset
uspto-grants-1991_10
Patent number
US05053409

Reaction notes

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