1,2-Dibromoethane → HCID 13061935, compound

HRID 344675Notes

Reaction equation

HRID 344675 reaction equation
[CH3:1][N:2]1[C:6]([S:7][CH2:8][CH2:9][Cl:10])=[N:5][N:4]=[N:3]1.C(OC(C1C=C(C(OCC)=O)NN=1)=O)C.Br[CH2:27][CH2:28][Cl:29].BrCCBr>>[CH3:1][N:2]1[C:6]([CH2:27][CH2:28][Cl:29])([S:7][CH2:8][CH2:9][Cl:10])[N:5]=[N:4][NH:3]1.[CH3:1][N:2]1[C:6]([S:7][CH2:8][CH2:9][Cl:10])=[N:5][N:4]=[N:3]1

Participants

6

Reactant 4

HCID 78391,2-DibromoethaneHCID 78491-Bromo-2-ChloroethaneHCID 142184diethyl 1H-pyrazole-3,5-dicarboxylateHCID 13061935HCID 13061935, compound

Product 2

HCID 13061935HCID 13061935, compoundHCID 86745115HCID 86745115, compound

Procedure

When an equivalent amount of 1-methyl-5-(2-chloroethylthio)-1H-tetrazole is substituted for 3,5-diethoxycarbonyl-1H-pyrazole and an equivalent amount of 2-bromochloroethane is substituted for 1,2-dibromoethane in the procedure of Example 4, 2-(1-methyl-5-(2-chloroethylthio)-1H-tetrazol-5-yl)ethyl chloride is isolated after column chromatography 1-methyl-5-(2-chloroethylthio)-1H-tetrazole, Aldrich, 59%, A).

Sources & evidence

ORD record
ord-33c63c1151b64ab8bcd70285ad388f45
Source dataset
uspto-grants-1991_10
Patent number
US05053411

Reaction notes

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