HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,5-Dimethylpyrazole → 3,5-Dimethylpyrazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,5-Dimethylpyrazole | HCID 6210 | — |
| Reactant | 1,2-Dibromoethane | HCID 7839 | — |
| Reactant | 1-Bromo-2-Chloroethane | HCID 7849 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3,5-Dimethylpyrazole | HCID 6210 | — |
| Product | 1-(2-chloroethyl)-3,5-dimethyl-1H-pyrazole | HCID 1149979 | — |
Reaction Steps
When an equivalent amount of 3,5-dimethylpyrazole is substituted for 1-ethoxycarbonyl-2H-indazolin-3-one and 2-bromochloroethane is substituted for 1,2-dibromoethane in the procedure of Example 19 using tetrahydrofuran as solvent, 2-(3,5-dimethyl-1H-pyrazol-1-yl)ethyl chloride is isolated after column chromatography (3,5-dimethylpyrazole, Aldrich, 24%, C).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05053411 |
| Source dataset | uspto-grants-1991_10 |
| ORD ID | ord-3a829151118043718252442deb88f81b |
| Source note | uspto-grants-1991_10 |