HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Dibromoethane → 1-Ebio
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Dibromoethane | HCID 7839 | — |
| Reactant | 1-Bromo-2-Chloroethane | HCID 7849 | — |
| Reactant | 1-Ebio | HCID 82320 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 1-Ebio | HCID 82320 | — |
| Product | 2-(3-ethyl-2,3-dihydro-2-oxo-1H-benzimidazol1-yl)ethyl chloride | HCID 15235716 | — |
Reaction Steps
When an equivalent amount of 3-ethyl-2-benzimidazolinone is substituted for 1-ethoxycarbonyl-2H-indazolin-3-one and 2-bromochloroethane is substituted for 1,2-dibromoethane in the procedure of Example 19 using tetrahydrofuran as solvent, 2-(3-ethyl-2,3-dihydro-2-oxo-1H-benzimidazol1-yl)ethyl chloride is isolated after column chromatography (3-ethyl-2-benzimidazolinone, Aldrich, 6%, A).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05053411 |
| Source dataset | uspto-grants-1991_10 |
| ORD ID | ord-d37a5e5e28b3461f99039a87156b426e |
| Source note | uspto-grants-1991_10 |