反应详情

5 g of 3-(5-methyloxazol-2-yl)-pyridine prepared as indicated in Chimica Therap 4, 437 (1973) is dissolved in 50 cm3 of ethanol, 3 cm3 of iodomethane is added and the whole is heated under reflux for 10 hours. After cooling and decanting, ether is added, and after filtering, 8.68 g of product is obtained. M.p.=147°-148° C., after crystallization from ethanol.

1. temperaturethe whole is heated
2. temperatureunder reflux for 10 hours
3. temperatureAfter cooling
4. customdecanting
5. additionether is added
6. filtrationafter filtering