HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → 1-Methyl-3-(5-methyloxazol-2-yl)-pyridinium iodide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | 5-Methyl-2-(3-pyridyl)-oxazole | HCID 19612507 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-Methyl-3-(5-methyloxazol-2-yl)-pyridinium iodide | HCID 67925080 | — |
Reaction Steps
5 g of 3-(5-methyloxazol-2-yl)-pyridine prepared as indicated in Chimica Therap 4, 437 (1973) is dissolved in 50 cm3 of ethanol, 3 cm3 of iodomethane is added and the whole is heated under reflux for 10 hours. After cooling and decanting, ether is added, and after filtering, 8.68 g of product is obtained. M.p.=147°-148° C., after crystallization from ethanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05053416 |
| Source dataset | uspto-grants-1991_10 |
| ORD ID | ord-51fd0243d6b04062a1810d51847ac00e |
| Source note | uspto-grants-1991_10 |