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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 344745Generated: October 26, 2026

Glycinamide hydrochloride → Dimiracetam

https://huagongshe.com/reaction/344745

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGlycinamide hydrochlorideHCID 2723639—
ReactantIsobutyl 4-oxobutanoateHCID 10464575—
ProductDimiracetamHCID 6595522.6%

Reaction Steps

Glycinamide hydrochloride (4.2 g, 38 mmol) and isobutyl 4-oxobutanoate (5 g, 31.6 mmol) were reacted together according to the procedure of example 2, to give the title compound 1 g (22.6%), m.p. 154°-157° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05053422
Source datasetuspto-grants-1991_10
ORD IDord-743505df9dcc4cf8a94543234b8b5e8f
Source noteuspto-grants-1991_10