反应详情

In 20 ml of acetone was dissolved 2.30 g of 1-methyl-3-piperidinol, and 3.72 g of methyl p-toluenesulfonate was added dropwise to the resulting solution. The mixture was stirred at room temperature, heated under reflux, and cooled to precipitate crystals. The crystals were collected by filtration and dried to give 4.94 g of the desired product, m.p. 125°-127° C. (decomp.).

1. additionwas added dropwise to the resulting solution
2. temperatureheated
3. temperatureunder reflux
4. temperaturecooled
5. customto precipitate crystals
6. filtrationThe crystals were collected by filtration
7. customdried