Potassium Acetate → HCID 15919157, compound

HRID 344801Notes

Reaction equation

HRID 344801 reaction equation
[CH2:1]([O:9][C:10]1[CH:15]=[CH:14][C:13]([C:16]2[N:21]=[C:20](Cl)[C:19]([C:23]([O-:25])=[O:24])=[CH:18][N:17]=2)=[CH:12][CH:11]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[C:26]([O-])(=O)[CH3:27].[K+]>C(O)C.[Pd].[O-]S([O-])(=O)=O.[Ba+2]>[CH2:1]([O:9][C:10]1[CH:15]=[CH:14][C:13]([C:16]2[N:21]=[CH:20][C:19]([C:23]([O:25][CH2:26][CH3:27])=[O:24])=[CH:18][N:17]=2)=[CH:12][CH:11]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

Participants

5

Reactant 2

HCID 517044Potassium AcetateHCID 86745123HCID 86745123, compound

Product 1

HCID 15919157HCID 15919157, compoundYield 93%

Reagents, catalysts & solvents 2

HCID 16218511Pd barium sulfateCatalystHCID 702EthanolSolvent

Procedure

Then, 4.9 g (0.012 mole) of the obtained 2-(p-octyloxyphenyl)-4-chloropyrimidine-5-carboxylate was dissolved in 100 ml of ethanol, and was reduced with 0.3 g of Pd/BaSO4 in the presence of potassium acetate to give 4.0 g of ethyl 2-(p-octyloxyphenyl)pyrimidine-5-carboxylate (yield: 93%).

Sources & evidence

ORD record
ord-bc645b85d0e14ae584a4cfa079f82265
Source dataset
uspto-grants-1991_10
Patent number
US05053507

Reaction notes

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