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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 344822Generated: October 29, 2026

Propionyl chloride → 1-Propanone, 1-(5-chloro-6-methoxy-2-naphthalenyl)-

https://huagongshe.com/reaction/344822

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropionyl chlorideHCID 62324—
ReactantAluminum(III) ChlorideHCID 6451240—
Reactant1-Chloro-2-methoxynaphthaleneHCID 11564623—
SolventDichloromethaneHCID 6344—
Product1-Propanone, 1-(5-chloro-6-methoxy-2-naphthalenyl)-HCID 10800601—

Reaction Steps

reacting under Friedel-Crafts conditions 1-chloro-2-methoxy-naphthalene with propionyl chloride in methylene chloride at a temperature of from about 0° C. to ambient temperature in the presence of aluminum chloride to form 1-(5-chloro-6-methoxy-2-naphthyl)-1-propanone,

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05053533
Source datasetuspto-grants-1991_10
ORD IDord-29c31bcb48824620869b75a57bd27925
Source noteuspto-grants-1991_10