Selenium Dioxide → 3-Methoxy-4-nitrophenylglyoxal

HRID 344869Notes

Reaction equation

HRID 344869 reaction equation
[CH3:1][C:2]([C:4]1[CH:9]=[CH:8][C:7]([N+:10]([O-:12])=[O:11])=[C:6]([O:13][CH3:14])[CH:5]=1)=[O:3].[Se](=O)=[O:16]>>[CH3:14][O:13][C:6]1[CH:5]=[C:4]([C:2]([CH:1]=[O:16])=[O:3])[CH:9]=[CH:8][C:7]=1[N+:10]([O-:12])=[O:11]

Participants

3

Reactant 2

HCID 24007Selenium DioxideHCID 116799901-(3-Methoxy-4-nitrophenyl)ethan-1-one

Product 1

HCID 543850723-Methoxy-4-nitrophenylglyoxal

Procedure

3-Methoxy-4-nitrophenylglyoxal was prepared according to the method described in Patent Application FR 2,351,108, but starting with 3-methoxy-4-nitroacetophenone (33.6 g) and selenium dioxide (22 g). The expected product (35 g) is obtained in the form of a brown oil, which was used without further purification for the subsequent steps.

Sources & evidence

ORD record
ord-de6cb35298a54f39818ffd6140f1a815
Source dataset
uspto-grants-1991_10
Patent number
US05053509

Reaction notes

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