反应详情

3.75 g of 4-hydroxybiphenyl-4'-carboxylic acid was heated under reflux together with (S)-2-methylbutyl alcohol in the presence of 0.10 g of p-toluenesulfonic acid for about 6 hours. Then the mixture was filtered to remove the unreacted 4-hydroxybiphenyl-4'-carboxylic acid. Next, the filtrate was evaporated and the unreacted (S)-2-methylbutyl alcohol was distilled off. The crystals thus obtained were recrystallized from 200 ml of n-hexane. Thus, 2.05 g of the corresponding colorless compound was obtained (Yield: 41%).

1. filtrationThen the mixture was filtered
2. customto remove the unreacted 4-hydroxybiphenyl-4'-carboxylic acid
3. customNext, the filtrate was evaporated
4. distillationthe unreacted (S)-2-methylbutyl alcohol was distilled off
5. customThe crystals thus obtained
6. customwere recrystallized from 200 ml of n-hexane