Toluene → HCID 178444428, compound

HRID 344984Notes

Reaction equation

HRID 344984 reaction equation
C(OC1C=CC([C:13]#[C:14][C:15]2[CH:20]=[CH:19][C:18]([S:21]([F:26])([F:25])([F:24])([F:23])[F:22])=[CH:17][CH:16]=2)=CC=1)CCCC.[C:27]1([CH3:33])[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1>[Pd]>[CH2:33]([C@H:27]1[CH2:32][CH2:31][C@H:30]([CH2:13][CH2:14][C:15]2[CH:20]=[CH:19][C:18]([S:21]([F:25])([F:26])([F:23])([F:24])[F:22])=[CH:17][CH:16]=2)[CH2:29][CH2:28]1)[CH2:13][CH2:14][CH2:15][CH3:16]

Participants

4

Reactant 2

HCID 1140TolueneHCID 867451284-(2-(4-Pentoxyphenyl)-ethynyl)-phenyl-sulfur pentafluoride

Product 1

HCID 178444428HCID 178444428, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

A mixture of 11.4 g of 4-(2-(4-trans-pentylcyclo-hexyl)-ethynyl)-phenyl sulfur pentafluoride (prepared as in EXAMPLE 7), 50 ml of toLuene and 10 mg of palladium-on-active charcoal is hydrogenated at room temperature under normal pressure. The solid constituents are filtered off and the filtrate is concentrated and worked up in the customary manner to give 4-(2-(trans-4-pentyl-cyclohexyl)-ethyl)-phenyl-sulfur pentafluoride.

Workup

  1. customis hydrogenated at room temperature under normal pressure
  2. filtrationThe solid constituents are filtered off
  3. concentrationthe filtrate is concentrated

Sources & evidence

ORD record
ord-1ca769012fb6453a8f69932cfa19f8f2
Source dataset
uspto-grants-1991_10
Patent number
US05055223

Reaction notes

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