Ethyl p-methylbenzenesulfonate → HCID 86745143, compound

HRID 345199Notes

Reaction equation

HRID 345199 reaction equation
[C:1]1([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:6]=[CH:5][C:4]([C:7]2[N:8]=[C:9]([CH3:12])[S:10][CH:11]=2)=[CH:3][CH:2]=1.[C:19]1([CH3:31])[CH:24]=[CH:23][C:22]([S:25]([O:28]CC)(=[O:27])=[O:26])=[CH:21][CH:20]=1>>[C:1]1([C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=2)[CH:6]=[CH:5][C:4]([C:7]2[N+:8]([CH2:19][CH3:20])=[C:9]([CH3:12])[S:10][CH:11]=2)=[CH:3][CH:2]=1.[CH3:31][C:19]1[CH:24]=[CH:23][C:22]([S:25]([OH:28])(=[O:27])=[O:26])=[CH:21][CH:20]=1

Participants

3

Reactant 2

HCID 6638Ethyl p-methylbenzenesulfonateHCID 906354-(4-Biphenylyl)-2-methyl-1,3-thiazole

Product 1

HCID 86745143HCID 86745143, compound

Procedure

4-(Biphenyl-4-yl)-2-methyl-thiazole (9.8 pbw) and ethyl p-toluenesulfonate (8.6 pbw) are stirred for 3 hours at 180° C. The hot mixture is poured onto acetone and further processed as described in Preparation Example 5(a).

Workup

  1. additionThe hot mixture is poured onto acetone
  2. customas described in Preparation Example 5(a)

Sources & evidence

ORD record
ord-f59042f79eae4811a8b040d8b0813e3c
Source dataset
uspto-grants-1991_10
Patent number
US05055579

Reaction notes

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