Benzyloxycarbonyl-L-phenylalanine → N-Benzyloxycarbonylphenylalanylalanine

HRID 345219Notes

Reaction equation

HRID 345219 reaction equation
[CH2:1]([O:8][C:9]([NH:11][C@H:12]([C:20]([OH:22])=O)[CH2:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.FC(F)(F)C(NCCC[CH2:31][C@@H:32]([C:34]([OH:36])=[O:35])[NH2:33])=O>>[CH2:1]([O:8][C:9]([NH:11][C@H:12]([C:20]([NH:33][C@H:32]([C:34]([OH:36])=[O:35])[CH3:31])=[O:22])[CH2:13][C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1)=[O:10])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 70878Benzyloxycarbonyl-L-phenylalanineHCID 7009573L-Lysine, N6-(trifluoroacetyl)-

Product 1

HCID 152128N-Benzyloxycarbonylphenylalanylalanine

Procedure

N-Benzyloxycaronbyl-L-phenylalanyl-Nε -trifluoroacetyl-L-lysine (m.p. 143°-147° C.) from N-benzyloxycarbonyl-L-phenylalanine and Nε -trifluoroacetyl-L-lysine (A. T. Moore, et al., J. Chem. Soc. (C), 2349-2359 (1966)).

Sources & evidence

ORD record
ord-990d53e519f24d848b9afbdf2d389c42
Source dataset
uspto-grants-1991_10
Patent number
US05055451

Reaction notes

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