Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 8-Oxo-2,2-dimethyl-7alpha-isopropyl-3-oxa-1-azabicyclo[4.2.0]octane | HCID 13051144 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 13051147 | HCID 13051147 | — |
Reaction Steps
8-oxo- 2,2-dimethyl-7α-isopropyl-3-oxa-1-azabicyclo[4.2.0]octane 1.0 g is dissolved in 8 ml of acetic acid and 2 ml H2O is added. The mixture is heated at 65° C. for 1.25 hrs. The acetic acid and H2O are removed under reduced pressure and the residue is taken up in C6H6 and evaporated to give 3-isopropyl-4-(2-hydroxyethyl)azetidinone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05055573 |
|---|
| Source dataset | uspto-grants-1991_10 |
|---|
| ORD ID | ord-80d5fcd7df9d43f78bf664def874a077 |
|---|
| Source note | uspto-grants-1991_10 |
|---|
