m-Chloroperbenzoic acid → HCID 19757849, compound

HRID 345336Notes

Reaction equation

HRID 345336 reaction equation
[CH2:1]([O:3][P:4]([C:9]1[CH:10]=[N:11][CH:12]=[CH:13][CH:14]=1)([O:6][CH2:7][CH3:8])=[O:5])[CH3:2].ClC1C=CC=C(C(OO)=[O:23])C=1>C(Cl)Cl>[CH2:1]([O:3][P:4]([C:9]1[CH:10]=[N+:11]([O-:23])[CH:12]=[CH:13][CH:14]=1)([O:6][CH2:7][CH3:8])=[O:5])[CH3:2]

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 10867660Diethyl pyridin-3-ylphosphonate

Product 1

HCID 19757849HCID 19757849, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A solution of 1.5g of 3-diethylphosphonopyridine, Bull. Chem. Soc. Jap. 55, 909 (1982), in 20 ml of methylene chloride is treated with 2.33g m-chloroperbenzoic acid at room temperature. The reaction mixture is allowed to stir at room temperature overnight, then concentrated under vacuum. The residue is partitioned between ether and water, the aqueous layer is concentrated under vacuum to afford 3-(diethylphosphono)-pyridine-N-oxide as a yellow oil.

Workup

  1. concentrationconcentrated under vacuum
  2. customThe residue is partitioned between ether and water
  3. concentrationthe aqueous layer is concentrated under vacuum

Sources & evidence

ORD record
ord-dd573d308bbd48dd8895d81014b79165
Source dataset
uspto-grants-1991_10
Patent number
US05057506

Reaction notes

Loading…