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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 345371Generated: October 30, 2026

1-(4-Iodophenyl)-4-propyl-3-trifluoromethyl-2,6,7-trioxabicyclo[2,2,2]octane → 1-[4-(3-Methoxyprop-1-ynyl)phenyl]-4-n-propyl-3-trifluoromethyl-2,6,7-trioxabicyclo[2,2,2]octane

https://huagongshe.com/reaction/345371

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Iodophenyl)-4-propyl-3-trifluoromethyl-2,6,7-trioxabicyclo[2,2,2]octaneHCID 15021959—
Reactant4-t-Butyl-1-[4-(3-methoxyprop-1-ynyl)phenyl]-2,6,7-trioxabicyclo[2,2,2]octaneHCID 15021966—
Product1-[4-(3-Methoxyprop-1-ynyl)phenyl]-4-n-propyl-3-trifluoromethyl-2,6,7-trioxabicyclo[2,2,2]octaneHCID 15021984—

Reaction Steps

1-[4-(3-Methoxyprop-1-ynyl)phenyl]-4-n-propyl-3-trifluoromethyl-2,6,7-trioxabicyclo[2,2,2]octane was prepared from 1-(4-iodophenyl)-4-n-propyl-3-trifluoromethyl-2,6,7-trioxabicyclo[2,2,2]octane and methyl propargyl ether using the methodology described in Example 3.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05057508
Source datasetuspto-grants-1991_10
ORD IDord-ae8e1fc030ee4d7eabd3a5f55e0a0411
Source noteuspto-grants-1991_10