反应详情

Trimethyl 4-bromo-orthobenzoate (1.5 g.) (McElvain and Venerable, J. Amer. Chem. Soc., 1950, 72, 1661) was added to 2-(2,2-dimethylpropyl)-2-hydroxymethyl-propan-1,3-diol (1.0 g.). One drop of concentrated hydrochloric acid was added and the mixture was maintained at 140° for one hour, under a current of nitrogen. The volatile components were removed in vacuo (1.0 mm), at 140° C.

1. temperaturethe mixture was maintained at 140° for one hour
2. customThe volatile components were removed in vacuo (1.0 mm), at 140° C.