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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 345422Generated: October 27, 2026

6-chloro-9-methyl-9H-purine → 6-Chloro-2,9-dimethyl-9H-purine

https://huagongshe.com/reaction/345422

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-chloro-9-methyl-9H-purineHCID 94844—
Reactant5-Amino-4-chloro-2-methyl-6-methylaminopyrimidineHCID 15016714—
Product6-Chloro-2,9-dimethyl-9H-purineHCID 1501671597%

Reaction Steps

This was prepared in a manner similar to that described in Example 9 for 6-chloro-9-methylpurine, except that 5-amino-4-chloro-2-methyl-6-methylaminopyrimidine was used as the starting material and the reaction was carried out at 60° C. for 6 hrs. The title compound was obtained in 97% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05057517
Source datasetuspto-grants-1991_10
ORD IDord-eb2e80a7f8994455ba4a6199d6b59f34
Source noteuspto-grants-1991_10