HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chloro-2,9-dimethyl-9H-purine → 6-Chloro-2-ethyl-9-methylpurine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chloro-2,9-dimethyl-9H-purine | HCID 15016715 | — |
| Reactant | 5-Amino-4-chloro-2-ethyl-6-methylaminopyrimidine | HCID 15016805 | — |
| Product | 6-Chloro-2-ethyl-9-methylpurine | HCID 15016806 | 65% |
Reaction Steps
This was prepared in a manner similar to that described in Example 27 for 6-chloro-2,9-dimethylpurine, except that 5-amino-4-chloro-2-ethyl-6-methylaminopyrimidine was used as the starting material, and the final product was purified by chromatography. The title compound was obtained in 65% yield. NMR (CDCl3, δ from TMS): 1.4 (t, CH2CH3), 3.06 (q, CH2CH3), 3.88 (s, NCH3), 8.00 (s, H8).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05057517 |
| Source dataset | uspto-grants-1991_10 |
| ORD ID | ord-1d289f5629d64267a6e5002b80c0f106 |
| Source note | uspto-grants-1991_10 |