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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 345656Generated: October 28, 2026

Ammonia → HCID 5327706, compound

https://huagongshe.com/reaction/345656

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
ReactantHCID 21615652HCID 21615652—
SolventDimethylformamideHCID 6228—
ProductHCID 5327706HCID 5327706—

Reaction Conditions

Temperature150 °C

Reaction Steps

0.30 g of 3-(1-methyl-3-indolyl)-4-(3-methylphenyl) furan-2,5-dione was treated with 8 ml of DMF and 60 ml of 33% aqueous ammonia and heated at 150° C. for 5 hours and then allowed to cool. The formed precipitate was filtered off, washed with water and dried to give 162 mg of 3-(1-methyl-3-indolyl)-4-(3-methylphenyl)-1H-pyrrole-2,5-dione, m.p. 243° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05057614
Source datasetuspto-grants-1991_10
ORD IDord-00008f917bc542ec87072683ed7dc023
Source noteuspto-grants-1991_10