Potassium Carbonate → HCID 15069997, compound

HRID 345797Notes

Reaction equation

HRID 345797 reaction equation
[CH3:1][N:2]1[O:9][CH2:8][CH:7]2[CH:3]1[CH2:4][N:5](C(OCC)=O)[CH2:6]2.C(=O)([O-])[O-].[K+].[K+]>O>[CH3:1][N:2]1[O:9][CH2:8][CH:7]2[CH:3]1[CH2:4][NH:5][CH2:6]2

Participants

4

Reactant 2

HCID 11430Potassium CarbonateHCID 15069996HCID 15069996, compound

Product 1

HCID 15069997HCID 15069997, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

13 g (65 mmol) of ethyl 2-methyl-3-oxa-2,7-diazabicyclo[3.3.0]octane-7-carboxylate are heated under reflux in 300 ml of water with 41 g of Ba(OH)2.8H2O overnight. Potassium carbonate is added, the barium carbonate which has precipitated out is filtered off with suction and the filtrate is extracted ten times with 100 ml of chloroform each time. The extract is dried over potassium carbonate and concentrated and the residue is distilled.

Workup

  1. customthe barium carbonate which has precipitated out
  2. filtrationis filtered off with suction
  3. extractionthe filtrate is extracted ten times with 100 ml of chloroform each time
  4. dry with materialThe extract is dried over potassium carbonate
  5. concentrationconcentrated
  6. distillationthe residue is distilled

Sources & evidence

ORD record
ord-a828fc3c88c34e6b8ebe6da3da0e0ca3
Source dataset
uspto-grants-1991_10
Patent number
US05059597

Reaction notes

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