反应详情

A solution of methyl 3-(5-trimethylsilyl-3-furyl)propionate (from above) in tetrahydrofuran (3 ml) was added dropwise to a suspension of lithium aluminum hydride (27 mg) in tetrahydrofuran (4 ml) at room temperature. After 3 hours, the mixture was quenched with ethyl acetate and extracted with ether. Evaporation of the dried (magnesium sulphate) extracts gave the title alcohol, which was used in the next step without purification.

1. customthe mixture was quenched with ethyl acetate
2. extractionextracted with ether
3. customEvaporation of the
4. dry with materialdried (magnesium sulphate)