反应详情

525 g of 2-nitro-4-methyl-5-fluoro-benzoic acid are hydrogenated in 3 l of dioxane with 50 g of 5% strength Pd-C catalyst at 30°-40° under 20-30 bar. The catalyst is filtered off with suction and the solution is poured onto water. The crystals which have precipitated are filtered off with suction and dried. Yield: 357 g (80.1% of theory), melting point: 201°-202° C.

1. filtrationThe catalyst is filtered off with suction
2. additionthe solution is poured onto water
3. customThe crystals which have precipitated
4. filtrationare filtered off with suction
5. customdried