Dimethylformamide dimethyl acetal → N-((dimethylamino)methylene) pyrazolo(1,5-a)pyrimidine-3-carboxamide
Reaction equation
[N:1]1[N:5]2[CH:6]=[CH:7][CH:8]=[N:9][C:4]2=[C:3]([C:10]([NH2:12])=[O:11])[CH:2]=1.[N:13]1[N:17]2[CH:18]=[CH:19][CH2:20][NH:21][C:16]2=[C:15]([C:22]([NH2:24])=[O:23])[CH:14]=1.CO[CH:27](OC)[N:28]([CH3:30])[CH3:29]>>[CH3:27][N:28]([CH:30]=[N:12][C:10]([C:3]1[CH:2]=[N:1][N:5]2[CH:6]=[CH:7][CH:8]=[N:9][C:4]=12)=[O:11])[CH3:29].[CH3:27][N:28]([CH:30]=[N:24][C:22]([C:15]1[CH:14]=[N:13][N:17]2[CH:18]=[CH:19][CH2:20][NH:21][C:16]=12)=[O:23])[CH3:29]Participants
5
Reactant 3
Product 2
Procedure
Other N-((dimethylamino)methylene)pyrazolo (1,5-a)-pyrimidine-3-carboxamide and N-((dimethylamino) methylene)-4,5-dihydropyrazolo(1,5-a)pyrimidine-3-carboxamide products which are prepared from corresponding pyrazolo(1,5-a)pyrimidine-3-carboxamide or the 4,5-dihydropyrazolo(1,5-a)pyrimidine-3-carboxamide intermediate compounds by heating with N,N-dimethylformamide dimethyl acetal in the manner described in Examples 20-22 are listed in Table IX.
Sources & evidence
- ORD record
- ord-03a0a661e25a49c8b1ebcf2d076fa29f
- Source dataset
- uspto-grants-1991_10
- Patent number
- US05059691
Reaction notes
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