Isopropylamine → 2,4-Bis-isopropylamino-6-(2,2,6,6-tetramethylpiperidin-1-yl)-1,3,5-triazine

HRID 345984Notes

Reaction equation

HRID 345984 reaction equation
Cl[C:2]1[N:7]=[C:6](Cl)[N:5]=[C:4]([N:9]2[C:14]([CH3:16])([CH3:15])[CH2:13][CH2:12][CH2:11][C:10]2([CH3:18])[CH3:17])[N:3]=1.[CH:19]([NH2:22])([CH3:21])[CH3:20]>C1(C)C(C)=CC=CC=1>[CH:19]([NH:22][C:2]1[N:7]=[C:6]([NH:9][CH:10]([CH3:17])[CH3:11])[N:5]=[C:4]([N:9]2[C:14]([CH3:16])([CH3:15])[CH2:13][CH2:12][CH2:11][C:10]2([CH3:18])[CH3:17])[N:3]=1)([CH3:21])[CH3:20]

Participants

4

Reactant 2

HCID 6363IsopropylamineHCID 199917662,4-Dichloro-6-(2,2,6,6-tetramethylpiperidin-1-yl)-1,3,5-triazine

Product 1

HCID 571741972,4-Bis-isopropylamino-6-(2,2,6,6-tetramethylpiperidin-1-yl)-1,3,5-triazine

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

43.4 g of 2,4-dichloro-6-(2,2,6,6-tetramethylpiperidin-1-yl)-1,3,5-triazine are heated in an autoclave to 160° for 8 hours with 39.0 g of isopropylamine in 200 ml of xylene. After cooling to room temperature, the autoclave contents are washed three times, each with 100 ml of water, and the yellowish xylene solution is dried over sodium sulfate, stirred for 10 minutes with 5 g of Tonsil Optimum (bleaching earth), filtered and evaporated. The 2,4-bis-isopropylamino-6-(2,2,6,6-tetramethylpiperidin-1-yl)-1,3,5-triazine obtained is a slightly yellowish resin which could not be crystallized.

Workup

  1. washthe autoclave contents are washed three times
  2. dry with materialeach with 100 ml of water, and the yellowish xylene solution is dried over sodium sulfate
  3. filtrationfiltered
  4. customevaporated

Sources & evidence

ORD record
ord-fbe136d2738c460ba442be3d2eca1780
Source dataset
uspto-grants-1991_10
Patent number
US05059689

Reaction notes

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