反应详情

Mix 0.034 mol of ethyl adamantane with a ten times excess of bromine (0.33 mol). Heat slowly and stir under reflux for 4 hrs. Then allow to cool and pour onto ice water. Decompose the excess bromine with sodium sulfite until discoloration of the aqueous solution. Subsequently extract with ether, wash the combined organic phases with sodium bicarbonate solution, dry with magnesium sulfate, filter and evaporate to dryness under vacuum. Recrystallize the residue from methanol. (Yield: 83%).

1. temperatureHeat slowly
2. temperatureunder reflux for 4 hrs
3. temperatureto cool
4. additionpour onto ice water
5. extractionSubsequently extract with ether
6. washwash the combined organic phases with sodium bicarbonate solution
7. dry with materialdry with magnesium sulfate
8. filtrationfilter
9. customevaporate to dryness under vacuum
10. customRecrystallize the residue from methanol