Sulfuric Acid → HCID 19990493, compound

Participants

Reaction Steps

Using the procedure described in Example 1, but replacing 2-phenyloxazolo[4,5-b]pyridine by 2-(2-fluorophenyl)oxazolo[5,4-b]pyridine (J. Med. Chem. 1978, 21, 11, 1158+) and using 8.4 ml of concentrated sulfuric acid in 16.8 ml of water and 16.8 ml of acetic acid, and after purification on a column of silica (40 to 63μ; 70-230 mesh; eluent: ethyl acetate/toluene, 1:9), the product of the title is obtained.

Provenance & Evidence