1,1'-Carbonyldiimidazole → HCID 54232870, compound

Participants

Reaction Steps

CDI (2.43 g, 0.015 moles) was added to 1.72 g (0.012 moles) of (pyrrolidin-2-one-1-yl) acetic acid in 40 ml of CH2Cl2 under stirring and after one hour morpholinocarbonylmethyl piperazine 2.56 g, 0.012 moles) was added. The solution was kept under stirring for 20 hours at room temperature, the solvent was then evaporated and the residue chromatographed on silica gel using CHCl3 --MeOH as eluant, ratio 95:5.

Provenance & Evidence