反应详情

To a solution of 6.87 g (0.043 mol) of 4-trifluoromethylaniline in 110 ml of dichloromethane was added 5.25 ml (0.043 mol) of pivaloylchloride. After stirring for 1.5 hours, 190 ml of a saturated solution of aqueous sodium bicarbonate was added. The reaction proceeded an additional 2 hours and the organic layer was separated and dried over anhydrous magnesium sulfate. The solution was filtered and the solvent removed to give the title compound, yield 9.16 g (88%), m.p. 154°-158° C.

1. waitThe reaction proceeded an additional 2 hours
2. customthe organic layer was separated
3. dry with materialdried over anhydrous magnesium sulfate
4. filtrationThe solution was filtered
5. customthe solvent removed