Guanidine Hydrochloride → N,N''-Dibutylguanidine

Temperature

120 °C

A mixture of guanidine hydrochloride (200 parts) and hexamethylene diamine (292 parts) were heated to 120° C. for 4 hours under a nitrogen atmosphere The temperature was then raised to 150–170° C. for a further 5 hours. The mixture was cooled to 80° C. and water (400 parts) was added, maintaining the temperature at 80° C. until dissolution occurred. The mixture was then cooled to give a solution in water of polyhexamethyleneguanidine, referred to as Prepolymer 1, having a weight average molecular weight (Mw) of 1010 and a number average molecular weight (Mn) of 710, as determined by aqueous gel permeation chromatography.

1. temperaturewas then raised to 150–170° C. for a further 5 hours
2. temperatureThe mixture was cooled to 80° C.
3. temperaturemaintaining the temperature at 80° C.
4. dissolutionuntil dissolution
5. temperatureThe mixture was then cooled

ORD record

ord-0423e525c6e84d15bca13a31ff875520

Source dataset

uspto-grants-2007_02

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US07172274B2