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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 346421Generated: October 29, 2026

N-Methylaniline → N-{4-[(3-iodophenyl)amino]quinazoline-6-yl}-4-(methylamino)-2-butenamide

https://huagongshe.com/reaction/346421

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-MethylanilineHCID 7515—
ReactantN-{4-[(3-iodophenyl)amino]quinazoline-6-yl}-4-(dimethylamino)-2-butenamideHCID 68562749—
ProductN-{4-[(3-iodophenyl)amino]quinazoline-6-yl}-4-(methylamino)-2-butenamideHCID 69420828—

Reaction Steps

N-{4-[(3-iodophenyl)amino]quinazoline-6-yl}-4-(methylamino)-2-butenamide was prepared as described above in Compound 5, using methylaniline instead of dimethylamine in step (ii).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07172749B2
Source datasetuspto-grants-2007_02
ORD IDord-bf068f66c82e4be791691495db42806e
Source noteuspto-grants-2007_02