L-Isoleucine → HCID 131726226, compound

HRID 346439Notes

Reaction equation

HRID 346439 reaction equation
[NH2:1][C@H:2]([C:7]([OH:9])=[O:8])[C@H:3]([CH2:5][CH3:6])[CH3:4].[CH2:10]([OH:32])[C@H:11]1[O:16][C@H:15]([O:17][C@H:18]2[C@H:23]([OH:24])[C@@H:22]([OH:25])[C@H:21]([OH:26])[O:20][C@@H:19]2[CH2:27][OH:28])[C@H:14]([OH:29])[C@@H:13]([OH:30])[C@@H:12]1[OH:31].O>>[CH2:10]([OH:32])[C@H:11]1[O:16][C@H:15]([O:17][C@H:18]2[C@H:23]([OH:24])[C@@H:22]([OH:25])[C@H:21]([OH:26])[O:20][C@@H:19]2[CH2:27][OH:28])[C@H:14]([OH:29])[C@@H:13]([OH:30])[C@@H:12]1[OH:31].[NH2:1][C@H:2]([C:7]([OH:9])=[O:8])[C@H:3]([CH2:5][CH3:6])[CH3:4]

Participants

3

Reactant 2

HCID 6306L-IsoleucineHCID 2723821(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol;hydrate

Product 1

HCID 131726226HCID 131726226, compound

Conditions

Temperature
20 °C

Procedure

Various amounts of L-isoleucine were added to a stock solution containing 50 mg maltose monohydrate per ml and the individual mixtures were dried at 20° C. An improved drying effect with an increasing amount of amino acid is clearly apparent. The addition of 20 mg/ml L-isoleucine (mixing ratio 5:2 by weight) increases the Tg of the maltose product by ca. 20° C. Table 5 shows the amount of L-isoleucine in the sugar solution and the resulting residual water content and the glass transition temperature Tg.

Workup

  1. customthe individual mixtures were dried at 20° C
  2. dry with materialAn improved drying effect with an increasing amount of amino acid
  3. additionThe addition of 20 mg/ml L-isoleucine (mixing ratio 5:2 by weight)

Sources & evidence

ORD record
ord-67fe491ac4844f8891e2491f0382b272
Source dataset
uspto-grants-2007_02
Patent number
US07172999B2

Reaction notes

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