huagongshe.com
HRID346463

反应详情

EQUATION

反应方程式

HRID 346463 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)O
HCID85083

1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-dimethylethyl) ester, (2S)-

C10H17NO4

结构：COC(=O)[C@@H]1CCCN1.Cl
HCID2733200

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)OC(C)(C)C
HCID14236281

未命名化合物

PROCEDURE

实验过程

2.15 g (10 mmol) BOC-L-proline and 1.66 g (10 mmol) proline methyl ester HCl salt were coupled according to procedure A. Yield of crude product 2.83 g. The product was purified with a silica column using 5% methanol in ethyl acetate as eluent. Yield 2.40 g (7.4 mmol, 74%)

WORKUP

后处理

  1. customThe product was purified with a silica column