HCID 178515985, compound → HCID 178515987, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 6-(6-chloro-1,2,4-triazolo[4,3-b]pyridazin-3-yl)pyridin-2-ol (960 mg) and piperidine (10 ml) was stirred at 100° C. for 3 hours. After allowing to cool to room temperature, the reaction solution was concentrated under reduced pressure, and the resultant crystalline residue was recrystallized from ethanol to obtain 6-(6-piperidin-1-yl-1,2,4-triazolo[4,3-b]pyridazin-3-yl) pyridin-2-ol (820 mg) as grayish white crystals.

Provenance & Evidence