Benzyl Chloride → Methyl 2-benzylmercapto-4-methyl-1,3-thiazol-5-ylacetate

HRID 34664Notes

Reaction equation

HRID 34664 reaction equation
[SH:1][C:2]1[S:3][C:4]([CH2:8][C:9]([O:11][CH3:12])=[O:10])=[C:5]([CH3:7])[N:6]=1.C(=O)([O-])[O-].[K+].[K+].[CH2:19](Cl)[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>CC(C)=O>[CH2:19]([S:1][C:2]1[S:3][C:4]([CH2:8][C:9]([O:11][CH3:12])=[O:10])=[C:5]([CH3:7])[N:6]=1)[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

5

Reactant 3

HCID 7503Benzyl ChlorideHCID 11430Potassium CarbonateHCID 178499653HCID 178499653, compound

Product 1

HCID 54499403Methyl 2-benzylmercapto-4-methyl-1,3-thiazol-5-ylacetate

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

2.03 g (0.01 mole) of methyl 2-mercapto-4-methyl-1,3thiazol-5-ylacetate are reacted with potassium carbonate and benzyl chloride in acetone and worked up in accordance with Example 1, stage 2.

Sources & evidence

ORD record
ord-7c0895af9d2c4df6ad329dd2873e4864
Source dataset
uspto-grants-1988_08
Patent number
US04762848

Reaction notes

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