1,3-Dibromopropane → 3-(4-Bromo-phenyl)-6-(3-bromo-propoxy)-benzo[d]isothiazole

HRID 347024Notes

Reaction equation

HRID 347024 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:12]3[CH:13]=[CH:14][C:15]([OH:17])=[CH:16][C:11]=3[S:10][N:9]=2)=[CH:4][CH:3]=1.[Br:18][CH2:19][CH2:20][CH2:21]Br>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[C:12]3[CH:13]=[CH:14][C:15]([O:17][CH2:21][CH2:20][CH2:19][Br:18])=[CH:16][C:11]=3[S:10][N:9]=2)=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 80011,3-DibromopropaneHCID 1358479523-(4-Bromo-phenyl)-benzo[d]isothiazol-6-ol

Product 1

HCID 223140693-(4-Bromo-phenyl)-6-(3-bromo-propoxy)-benzo[d]isothiazole

Procedure

In analogy to example 2.1, 3-(4-bromo-phenyl)-benzo[d]isothiazol-6-ol and 1,3-dibromopropane were converted to yield 3-(4-Bromo-phenyl)-6-(3-bromo-propoxy)-benzo[d]isothiazole as yellow oil, MS: 425 (M, 2Br).

Sources & evidence

ORD record
ord-9d09a97314774c2ab021d1c9560b62f7
Source dataset
uspto-grants-2007_02
Patent number
US07173043B2

Reaction notes

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