Piperidine → HCID 22314140, compound
Reaction equation
Br[CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]1[CH:25]=[CH:24][C:10]2[C:11]([C:14]3[CH:19]=[CH:18][C:17]([C:20]([F:23])([F:22])[F:21])=[CH:16][CH:15]=3)=[N:12][S:13][C:9]=2[CH:8]=1.[NH:26]1[CH2:31][CH2:30][CH2:29][CH2:28][CH2:27]1>>[N:26]1([CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]2[CH:25]=[CH:24][C:10]3[C:11]([C:14]4[CH:19]=[CH:18][C:17]([C:20]([F:23])([F:22])[F:21])=[CH:16][CH:15]=4)=[N:12][S:13][C:9]=3[CH:8]=2)[CH2:31][CH2:30][CH2:29][CH2:28][CH2:27]1Participants
3
Procedure
According to the method in example 7, 6-(4-Bromo-butoxy)-3-(4-trifluoromethyl-phenyl)-benzo[d]isothiazole and Piperidine were converted to yield 6-(4-Piperidin-1-yl-butoxy)-3-(4-trifluoromethyl-phenyl)-benzo[d]isothiazole, MS: 435 (MH+).
Sources & evidence
- ORD record
- ord-ef1ff86e7b49467db2420db99e57b5a9
- Source dataset
- uspto-grants-2007_02
- Patent number
- US07173043B2
Reaction notes
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