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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 347278Generated: October 30, 2026

2-Chlorobenzothiazole → 2-(s)-(Benzothiazol-2-ylamino)-3-cyclohexyl-n-[2-(5-fluoro-2,3-dihydro-indol-1-yl)-ethyl]-propionamide

https://huagongshe.com/reaction/347278

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-ChlorobenzothiazoleHCID 11987—
Reactant3-Cyclohexyl-L-alanineHCID 712421—
Reactant1H-Indole-1-ethanamine, 5-fluoro-2,3-dihydro-HCID 21082249—
Product2-(s)-(Benzothiazol-2-ylamino)-3-cyclohexyl-n-[2-(5-fluoro-2,3-dihydro-indol-1-yl)-ethyl]-propionamideHCID 11397166—

Reaction Steps

The title compound was prepared from 2-chlorobenzothiazole, L-cyclohexylalanine and 2-(5-fluoro-2,3-dihydro-indol-1-yl)-ethylamine using the procedure analogous to that described in example 2. HPLC-MS calcd. for C26H31FN4OS (M+H+) 467.22. found 467.5.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07173051B2
Source datasetuspto-grants-2007_02
ORD IDord-5850f966bf664b14a23d5ca0bcefb8d6
Source noteuspto-grants-2007_02