Pyrrolidine → HCID 23064283, compound

HRID 347585Notes

Reaction equation

HRID 347585 reaction equation
[NH:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1.Cl[C:7]1[C:12]([N+:13]([O-:15])=[O:14])=[CH:11][C:10]([N+:16]([O-:18])=[O:17])=[CH:9][N:8]=1>O1CCOCC1>[N+:16]([C:10]1[C:9]([N:1]2[CH2:5][CH2:4][CH2:3][CH2:2]2)=[N:8][CH:7]=[C:12]([N+:13]([O-:15])=[O:14])[CH:11]=1)([O-:18])=[O:17]

Participants

4

Reactant 2

HCID 31268PyrrolidineHCID 757382-Chloro-3,5-dinitropyridine

Product 1

HCID 23064283HCID 23064283, compoundYield 89.6%

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Conditions

Temperature
60 °C

Procedure

2.2 g (0.03 mol) of pyrrolidine were added over 10 minutes to a solution containing 3 g (0.015 mol) of 2-chloro-3,5-dinitropyridine in 30 ml of dioxane, at 40° C. The reaction medium was maintained at 60° C. until the reagents disappeared. The reaction medium was then poured into a water/ice mixture with vigorous stirring and the precipitate was filtered off by suction, washed with water and then dried to constant weight to give 3.2 g of 3,5-dinitro-2-pyrrolidin-1-ylpyridine.

Workup

  1. customat 40° C
  2. filtrationthe precipitate was filtered off by suction
  3. washwashed with water
  4. customdried to constant weight

Sources & evidence

ORD record
ord-32f0a6921d50413cb70ab9d437f4c2c8
Source dataset
uspto-grants-2007_02
Patent number
US07175670B2

Reaction notes

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