2-Methylpiperidine → HCID 21082848, compound

HRID 347594Notes

Reaction equation

HRID 347594 reaction equation
Cl[C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([N+:11]([O-:13])=[O:12])=[CH:4][N:3]=1.[CH3:14][CH:15]1[CH2:20][CH2:19][CH2:18][CH2:17][NH:16]1>C1COCC1>[CH3:14][CH:15]1[CH2:20][CH2:19][CH2:18][CH2:17][N:16]1[C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([N+:11]([O-:13])=[O:12])=[CH:4][N:3]=1

Participants

4

Reactant 2

HCID 79742-MethylpiperidineHCID 757382-Chloro-3,5-dinitropyridine

Product 1

HCID 21082848HCID 21082848, compoundYield 94.5%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Conditions

Temperature
60 °C

Procedure

2.5 g (12.28 mmol) of 2-chloro-3,5-dinitropyridine, 10 ml of THF and 25 mmol of 2-methylpiperidine were placed in a round-bottomed flask. The mixture was maintained at 60° C. for 15 hours with stirring and was then poured into an ice-water mixture with stirring. The precipitate formed was filtered off by suction and dried under vacuum to constant weight. 3.09 g of yellow powder were obtained.

Workup

  1. stirringwith stirring
  2. customThe precipitate formed
  3. filtrationwas filtered off by suction
  4. customdried under vacuum to constant weight

Sources & evidence

ORD record
ord-5b26e16b1b334ef39e0304ad49777e04
Source dataset
uspto-grants-2007_02
Patent number
US07175670B2

Reaction notes

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