反应详情

0.42 g (2.0 mmol) of N,N′-diisopropyl selenourea were dissolved in 20 mL of tetrahydrofuran. 0.08 mL (1.0 mmol) of chloroacetyl chloride were added to the solution, and after stirring well, the mixture was allowed to react at 0 degrees Celsius for one hour. 0.09 mL (1.0 mmol) of pyridine was then added to the reaction mixture, followed by stirring at 0 degrees Celsius for additional 2 hours. The reaction mixture was extracted by an ordinary method, washed with water and dried, and the solvent was distilled off. As a result, 0.25 g of 3-isopropyl-2-isopropylimino-1,3-selenazolidin-4-one were obtained. The purity was 98.7%, and the yield was 100%.

1. customto react at 0 degrees Celsius for one hour
2. stirringby stirring at 0 degrees Celsius for additional 2 hours
3. extractionThe reaction mixture was extracted by an ordinary method
4. washwashed with water
5. customdried
6. distillationthe solvent was distilled off