HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-methyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one → 1-Methyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-methyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one | HCID 21083258 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Product | 1-Methyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine | HCID 11961606 | — |
Reaction Steps
1-Methyl-2-oxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine from Example 18A (1.7 g, 9.65 mmol) was reduced with lithium aluminium hydride according to the procedure in Example 15A; yield 1.34 g (86%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07176195B2 |
| Source dataset | uspto-grants-2007_02 |
| ORD ID | ord-9ac33bcb55ff491595209dfc2f1bc2d1 |
| Source note | uspto-grants-2007_02 |