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HRID347648

反应详情

EQUATION

反应方程式

HRID 347648 的结构方程式

REACTANTS

反应物

2
结构：Cc1cc(C(=O)O)ccc1C#N
HCID10241099

4-cyano-3-methylbenzoic acid

C9H7NO2

结构：CCN1CCCNc2ccccc21
HCID19608231

未命名化合物

PRODUCTS

生成物

1
结构：CCN1CCCN(C(=O)c2ccc(C#N)c(C)c2)c2ccccc21
HCID21083244

未命名化合物

PROCEDURE

实验过程

The carboxylic acid from Example C (0.53 g, 3.29 mmol) was reacted with 1-ethyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine from Example 23B (0.514 g, 2.92 mmol) according to the procedure in Example 1A. The product was purified by flash chromatography on silica (eluant EtOAc:pet. ether 60:40); yield 0.55 g (59%).

WORKUP

后处理

  1. customThe product was purified by flash chromatography on silica (eluant EtOAc:pet. ether 60:40)