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HRID347649

反应详情

EQUATION

反应方程式

HRID 347649 的结构方程式

REACTANTS

反应物

2
结构：c1ccc2c(c1)NCCCS2
HCID93963

2,3,4,5-tetrahydro-1,5-benzothiazepine

C9H11NS

结构：Cc1cc(C(=O)O)ccc1C#N
HCID10241099

4-cyano-3-methylbenzoic acid

C9H7NO2

PRODUCTS

生成物

1
结构：Cc1cc(C(=O)N2CCCSc3ccccc32)ccc1C#N
HCID21083271

未命名化合物

PROCEDURE

实验过程

The carboxylic acid from Example C (0.27 g; 1.68 mmol) was reacted with 2,3,4,5-tetrahydro-1,5-benzothiazepine (0.28 g, 1.70 mmol) according to the procedure in Example 1A. The product was purified by flash chromatography on silica (eluant EtOAc:pet. ether 60:40); yield 0.43 g (84%).

WORKUP

后处理

  1. customThe product was purified by flash chromatography on silica (eluant EtOAc:pet. ether 60:40)