Sodium Hydroxide → HCID 21083632, compound

Participants

Reaction Conditions

Reaction Steps

Methyl 3-[3-[N-(3-pyridylmethyl)carbamoyl]-4-methoxy-phenyl]propionate (200 mg, 0.609 mmol), 10 mL of methanol and 10 mL of 1 mol/L aqueous solution of sodium hydroxide were mixed and, after stirring for 4 hours at 60° C., the reaction mixture was concentrated under reduced pressure. The residue was neutralized with. 2 mol/L hydrochloric acid under cooling with ice. The precipitates produced were filtered and dried to obtain 90.0 mg (47%) of the title compound as colorless powder.

Provenance & Evidence