HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 58801124, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2-Amino-4-chloro-6-methylpyrimidine | HCID 21810 | — |
| Reactant | Ethyl 4-piperidinecarboxylate | HCID 70770 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 58801124 | HCID 58801124 | — |
Reaction Steps
A solution of 4-piperidinecarboxylic acid ethyl ester (6.6 g), 2-amino-4-chloro-6-methylpyrimidine (5.0 g) and triethylamine (4.2 g) in ethanol (50 ml) is stirred at 90° C. for 3 hours. Ethanol is evaporated under reduced pressure, and the residue is dissolved in chloroform, and washed with water. The organic layer is concentrated under reduced pressure to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07176199B2 |
| Source dataset | uspto-grants-2007_02 |
| ORD ID | ord-d2703f16d5d74007a07415b5d572fb51 |
| Source note | uspto-grants-2007_02 |